COVID-19 Pandemic, Corona Viruses, and Diabetes Mellitus.
Identifieur interne : 000283 ( Main/Exploration ); précédent : 000282; suivant : 000284COVID-19 Pandemic, Corona Viruses, and Diabetes Mellitus.
Auteurs : Ranganath Muniyappa [États-Unis] ; Sriram Gubbi [États-Unis]Source :
- American journal of physiology. Endocrinology and metabolism [ 1522-1555 ] ; 2020.
Abstract
The pandemic of COVID-19, a disease caused by a novel coronavirus (CoV), SARS-CoV-2, is causing substantial morbidity and mortality. Older age and presence of diabetes mellitus, hypertension, and obesity significantly increases the risk for hospitalization and death in COVID-19 patients. In this Perspective, informed by the studies on severe acute respiratory syndrome, SARS-CoV, and Middle East respiratory syndrome, MERS-CoV, and the current literature on SARS-CoV-2, we discuss potential mechanisms by which diabetes modulates the host-viral interactions and host-immune responses. We hope to highlight gaps in knowledge that require further studies pertinent to COVID-19 in patients with diabetes.
DOI: 10.1152/ajpendo.00124.2020
PubMed: 32228322
Affiliations:
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Endocrinology and metabolism</title><idno type="eISSN">1522-1555</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The pandemic of COVID-19, a disease caused by a novel coronavirus (CoV), SARS-CoV-2, is causing substantial morbidity and mortality. Older age and presence of diabetes mellitus, hypertension, and obesity significantly increases the risk for hospitalization and death in COVID-19 patients. In this Perspective, informed by the studies on severe acute respiratory syndrome, SARS-CoV, and Middle East respiratory syndrome, MERS-CoV, and the current literature on SARS-CoV-2, we discuss potential mechanisms by which diabetes modulates the host-viral interactions and host-immune responses. We hope to highlight gaps in knowledge that require further studies pertinent to COVID-19 in patients with diabetes.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Maryland</li></region></list><tree><country name="États-Unis"><region name="Maryland"><name sortKey="Muniyappa, Ranganath" sort="Muniyappa, Ranganath" uniqKey="Muniyappa R" first="Ranganath" last="Muniyappa">Ranganath Muniyappa</name></region><name sortKey="Gubbi, Sriram" sort="Gubbi, Sriram" uniqKey="Gubbi S" first="Sriram" last="Gubbi">Sriram Gubbi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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